Medical Research & News

Through a collaborative approach to research support, the Foundation is focused on improving diagnosis, treatment therapies, better understanding of the disease burden, and advocating for increased research funding that can benefit patients --- with an ultimate goal of helping researchers find a cure for cutaneous lymphoma.

Research

Epigenetics & Biology of Cutaneous T-cell Lymphomas
These are exciting times in cutaneous T-cell lymphoma (CTCL) research. The hard work of laboratory and clinical investigators worldwide is starting to bear fruit, and a number of basic discoveries in the genetic and epigenetic foundations of CTCL are now being translated into novel therapies, with great impact for patients.
Research

Medical Meeting Highlights: 3rd World Congress, T-Cell Lymphoma Forum and USCLC Annual Workshop
In a world that has 7,000 known rare diseases, with only 5% having any treatment available, the future of discovery and new treatment development in cutaneous lymphoma is promising. There is much hope for a brighter future for everyone living with this condition.
Research

Interleukin-13 is over-expressed in cutaneous T-cell lymphoma cells and regulates their proliferation
Cutaneous T-cell lymphomas (CTCLs) primarily affect skin and are characterized by proliferation of mature CD4+ T-helper cells. The pattern of cytokine production in the skin and blood is considered to be of major importance for the pathogenesis of CTCLs.
Key Points:
IL-13 is an autocrine factor for CTCL.
IL-13 and its receptors represent novel markers of CTCL malignancy and potential therapeutic targets for intervention.
Research

Novel Tumor Markers for CTCL Identified
IL-13 has been identified as an autocrine factor for cutaneous T-cell lymphomas (CTCL) and its receptors may be novel tumor markers for the disease, serving as potential therapeutic targets, results of a study published recently in Blood showed.
Research

Low-dose total skin electron beam therapy
Low-dose total skin electron beam therapy as an effective modality to reduce disease burden in patients with mycosis fungoides: Results of a pooled analysis from 3 phase-II clinical trials.
Research

CLARIONS Recipient Presents Research Abstract
2014 CLARIONS Research Award recipient Tae Jin Kim, PhD has had his abstract titled Flexible Dosimeter Bands for Whole-Body Dosimetry  accepted for an oral presentation at AAPM (The American Association of Physicists in Medicine) 58th Annual Meeting & Exhibition. The focus of Dr. Kim's research is developing a flexible radiation detector (dosimeter), which he has tested on a preclinical X-ray system, and is currently designing a readout device. Dr. Kim is a Postdoctoral Fellow in the Department of Radiation Oncology (Medical Physics) at Stanford University School of Medicine.

The Cutaneous Lymphoma Foundation is pleased to support this ground-breaking research through our CLARIONS Research Award Program.
Answers from the Experts

FUTURE DIRECTIONS IN T-CELL CUTANEOUS LYMPHOMA
Advances are being made in improving diagnostic tools. Dr. Christiane Quelfeld presents what has become available and what the future holds.