Medical Research & News

Through a collaborative approach to research support, the Foundation is focused on improving diagnosis, treatment therapies, better understanding of the disease burden, and advocating for increased research funding that can benefit patients --- with an ultimate goal of helping researchers find a cure for cutaneous lymphoma.

Panel Discussion: TELLOMAK Clinical Trial Update

June 2022:  Drs. Pierluigi Porcu and Martine Bagot discuss the history of lacutamab (TELLOMAK) for treating CTCL and provide an update on the phase two clinical trial. Hear from the original researchers on how it started and where it is now.

Researchers
Pierluigi Porcu, MD
Professor of Medical
Oncology, Dermatology, and Cutaneous Biology Director, Division of Hematologic Malignancies
Sidney Kimmel Cancer Center
Philadelphia, Pennsylvania

Martine Bagot, PhD
Professor and Head of Department of Dermatology
Hôpital Saint Louis
Paris, France

EORTC-CLG Annual Scientific Meeting Highlights

October 2021 - Highlights from the 2021 EORTC-CLG Scientific Meeting clinical presentations

Panel Discussion: TELLOMAK Clinical Trial

May 2021: A panel discussion about the TELLOMAK clinical trial evaluating lacutamab in patients with advanced T-cell lymphomas, including Sézary syndrome and mycosis fungoides. Dr. Youn Kim and Dr. Joyson Karakunnel join Susan Thornton to discuss the clinical perspective of the study, where the study is today, preliminary data to share from the trial and more.

Panelists: 
Joyson Karakunnel, MD, MSc, FACP, Innate Pharma 
Youn Kim, MD, Stanford Health Care
Susan Thornton, CEO, Cutaneous Lymphoma Foundation

Panel Discussion: FLASH Clinical Trial Update

June 2020: The FLASH (Fluorescent Light Activated Synthetic Hypericin) Study, a phase 3 trial by Soligenix, is a potential new treatment for early stage cutaneous lymphoma using visible fluorescent light. Susan Thornton, CEO, was joined by Drs. Ellen Kim, Chris Pullion and Richard Straube to discuss this exciting technology.

Panelists:
Ellen Kim, MD, Medical Director, Dermatology Clinic, Perelman Center for Advanced Medicine
Richard Straub, MD, Chief Medical Officer, Soligenix, Inc.
Chris Pullion, DO, Medical Director, Soligenix Inc.

Helsinn Therapeutics (U.S.), Inc. waives copay fees for cancer-treating drug VALCHLOR®

April 2020 - Helsinn Therapeutics (U.S.), Inc., the US subsidiary of the Swiss pharmaceutical group focused on building quality cancer care products, today announces a change to the financial assistance program for VALCHLOR® (mechlorethamine) gel 0.016% to ensure that commercially insured patients have access to treatment during the COVID-19 crisis.

FLASH Clinical Trial- Update

Positive results were announced earlier this year for the FLASH Study, a phase 3 clinical trial in CTCL, by Soligenix. SGX301 is a novel first-in-class photodynamic therapy utilizing safe visible light for activation.

American Society of Hematology Announces 2020 Scholar Award Recipients

December 2019 - The American Society of Hematology (ASH) announced the 39 recipients of its 2020 Scholar Awards. One of ASH’s most prestigious research award programs, the ASH Scholar Awards financially support fellows to junior faculty dedicated to careers in hematology research as they transition from training programs to careers as independent investigators. Awardees included cutaneous lymphoma researcher, Anjali Mishra, PhD. 

FDA Approves Mogamulizumab for CTCL

The FDA has approved mogamulizumab-kpkc (Poteligeo) for the treatment of patients with cutaneous T-cell lymphoma (CTCL) who have received at least 1 prior systemic therapy.

Research in Cutaneous Lymphoma: A Broad View

Since the development of the “scientific method,” people have been engaged in research in efforts to answer questions, solve problems, and add to our overall knowledge. Nowhere is this more evident than in the medical field, and in the study of cutaneous lymphoma.

FLASH Study: Clinical Trial Update

Dr. Ellen Kim shares information about the role of clinical trials and specifically the FLASH [Fluorescent Light Activated Synthetic Hypericin] Study.

Protein Can Help Identify Which Rashes Are Early Mycosis Fungoides

Chronic rash in a sun-protected area that doesn’t respond to topical treatment likely needs to be evaluated for mycosis fungoides, the most common variant of cutaneous T-cell lymphoma. Now, a new VA study reports that a protein expression can help make the diagnosis.

Skin-Directed Tactics Optimal for Early Cutaneous Lymphoma

For patients with early-stage cutaneous lymphoma, skin-directed treatments, such as topical steroids and phototherapy, can slow or halt progression, but patients are also being treated with systemic therapies, according to the first-of-its kind research on this rare malignancy.

FUTURE DIRECTIONS IN T-CELL CUTANEOUS LYMPHOMA

Advances are being made in improving diagnostic tools. Dr. Christiane Quelfeld presents what has become available and what the future holds.

WHAT ARE FOCUS AREAS IN CUTANEOUS LYMPHOMA RESEARCH?

New breakthroughs in research offer hope of better treatments and may offer insight into the causes of cutaneous lymphoma.